Published on September 19, 2018 at 6:00PM Pacific |

| Film (Distributor) | Weekend Gross |
Total Gross |
% Change |
Week # |
|
| 1 | The House with a Clock in Its Walls (Universal) |
$21.7 M | $21.7 M | NEW | 1 |
| 2 | The Predator (Fox) | $9.3 M | $41.3 M | -62% | 2 |
| 3 | A Simple Favor (Lionsgate) | $8.8 M | $31.0 M | -45% | 2 |
| 4 | The Nun (Warner / New Line) | $8.3 M | $99.2 M | -54% | 3 |
| 5 | Fahrenheit 11/9 (Briarcliff) | $6.0 M | $6.0 M | NEW | 1 |
| 6 | Crazy Rich Asians (Warner Bros.) | $5.9 M | $158.8 M | -32% | 6 |
| 7 | White Boy Rick (Sony / Studio 8) | $4.8 M | $17.3 M | -46% | 2 |
| 8 | Life Itself (Amazon Studios) | $4.7 M | $4.7 M | NEW | 1 |
| 9 | Peppermint (STXfilms) | $3.2 M | $29.9 M | -47% | 3 |
| 10 | The Meg (Warner Bros.) | $2.4 M | $140.6 M | -38% | 7 |
| 11 | Assassination Nation (NEON) | $2.3 M | $2.3 M | NEW | 1 |
| 12 | Searching (Sony / Screen Gems) | $2.2 M | $23.2 M | -31% | 5 |
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| Film (Distributor) | Opening Weekend |
YT Trailer Views |
OW to YT Ratio |
| The House with a Clock in Its Walls (UNI) | $21.700 M | 7.452 M | 2.912 |
| Comparisons | |||
| Hotel Transylvania 3 (SNY) | $44.076 M | 17.266 M | 2.553 |
| A Wrinkle in Time (DIS) | $33.124 M | 10.271 M | 3.225 |
| Wonder (LGF) | $27.548 M | 8.045 M | 3.424 |
| Captain Underpants (FOX/DWA) | $23.852 M | 8.725 M | 2.734 |
| Fahrenheit 11/9 (BRI) | $6.000 M | 2.508 M | 2.392 |
| Comparisons | |||
| Chappaquiddick (ESMP) | $5.766 M | 2.415 M | 2.387 |
| The Post (FOX/DW) | $19.362 M | 12.918 M | 1.499 |
| Three Billboards (FSL) | $4.403 M | 1.518 M | 2.901 |
| Battle of the Sexes (FSL) | $3.409 M | 1.646 M | 2.071 |
| Life Itself (AMA) | $4.700 M | 12.590 M | 0.373 |
| Comparisons | |||
| Operation Finale (MGM) | $6.023 M | 10.716 M | 0.562 |
| Dog Days (LDE) | $2.555 M | 7.384 M | 0.346 |
| Megan Leavey (BS) | $3.811 M | 10.099 M | 0.377 |
| The Promise (OR) | $4.096 M | 6.354 M | 0.645 |
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